She’s got the curves

Curves that move when she moves

Curves that move from the gloom inside my room

To bewildered to know just what to do

Entranced by the curves that make up you

I start singing she’s got the curves

Youth is wasted on the young, and a woman’s figure starts to falter around age forty.  A personal physician prescribes Premarin for women to maintain their female habitus.   Let us look closer to see what the doctor is giving her.  Premarin or conjugated estrogen is an estrogen molecule with an ethinyl substituent at carbon 21.  The addend is a triple bonded sp1 hybridization that adds or eliminates in the appropriate environment.  This added makes Premarin less susceptible to degradation or conjugation by hepatic enzymes.  In addition, the triple bond adds to the DNA initiator site in a 60S Svedberg system and won’t let go.   In a mammalian transcription system, this means DNA replication rather than being induced and finite becomes constitutive.  In the cancer zoo at the Big U, monkeys develop huge fluctuant carcinomas when maintained on mega doses of Premarin.  Why then do physicians prescribe Premarin?

Physicians prescribe oral Premarin because the liver has trouble breaking the molecule down for elimination.  This means easy and convenient dosing and the woman maintains secondary sexual characteristics, or so it seems.

Expert organic chemist makes a lot of money, adding here, subtracting there, or causing gross elimination to unsubstituted nuclei.  Current birth control pills use chemically modified androgens as a pregestational agent because androgens are excreted in great quantity from horse urine.  If it makes money it goes, and the nation has an economy based on the acceptance of substances offered by the AMA. 

The main action of estrogen is sodium ion influx into cells.  This is why a fertile woman feels soft, silky, and supple.  In addition, the DNA replication induced by the steroid drug causes the proliferation of cells that are sensitive to estrogens and estrogen-like substances like the uterus and breast.  This is why women who chronically ingest birth control pills for inane reasons have large breasts.   If a woman wants to grow large breasts, they just have to get on birth control.  The main function of estrogen is to stimulate the growth of the epithelia in the uterus so it can maintain a fetus in a pregnancy.  Progesterone which is 21 hydroxy steroid caps off the proliferation by maintaining the uterine stroma and the fetus can develop. The main difference between estrogen and progesterone is the cyclization of the benzene group in the per phenanthrene molecule. When the estrogen feeds back into the ovarian operon, steroid production ceases, and a woman cycles.  If a pregnancy happens, and they do very often, the corpus luteum of the developing syncytial cytotrophoblast begins producing estrogen to maintain the placenta and the baby grows.

What is the solution?   The solution is to give estrogen by injection which few people except insulin diabetics can tolerate.  There might exist another solution in the plant world.  Hearsay and old wife’s tales stipulate that an estrogen-like substance occurs in eggplant.    A woman who desires curves can juice or cook eggplant daily in direct relation to her cycle.   The world seeks a botanist to come up with a suitable estrogen-containing plant that can be extracted, concentrated, and purified for mature women in middle age and beyond.  The world is waiting, there is a lot of work to be done.  Consult old Indian herbalist guides and inquire from doctors practicing traditional Chinese medicine about what avenues to pursue.  Hope springs eternal and she has the curves.