Until the twentieth century, cancer was a rare disease.  It occurred mainly in chimney sweeps, metal workers, and alchemists.  Now, in modern society, cancer pervades our every consciousness, infects our children, and shortens our life span.   Cancer is completely avoidable and results from exposure to chemicals, radiation, and viruses.   Massive or cumulative accumulation of radiation or infection by rare and usually unknown viruses may induce cancer, but the main culprits are organic chemicals.   In Cotran-Clinical Pathology, a timeline reveals the exponential increase in leukemia during the twentieth century. Cells that divide quickly, like white blood cells seem more prone to developing cancer.

The main offenders in the development of cancer are organic chemicals.   As petroleum and the energy that it confers, the plastics that it makes, and the pharmaceuticals it does convene, use increases, so does the incidence of cancer.  Medical drugs, like heart drugs and anti-hypertensive agents, produced by medical corporations, act as Grignard addition reactants to the DNA and induce cancer.  On a molecular scale, active transcribing DNA in a cell, which makes proteins conferring a cell identity, becomes inoperable due to petroleum chemical addends, the cell reverts to a more primitive gene product in the chromosomes, one that mandates uncontrolled growth like a developing organ in a child.  The proteins a cell makes confer the identity and function of that cell.  Acid proteins and histones strip from the DNA on a chromosome permitting the DNA to translate into protein.  This translatable DNA is chemically reactive, and if destroyed by chemicals, the cell unmasks new genes on new chromosomes, by stripping histones and acid protein, and the cell to survive becomes cancer.  Cancer is uncontrolled growth, a condition resembling primitive embryonic cells in the womb. 

Cells have protein on their surface produced by DNA that reveals the cell’s identity.  As a tangential reference to oncogenesis, a fetus in a womb causes the mother to produce antibodies to the fetus and these antibodies, used in tissue typing are HLA antigens.  The mother produces antibodies to the developing child and when this response becomes paramount, the body induces birth or in an immunologic sense, a rejection of the child by the body.  Similarly with cancer, if a patient fights cancer long enough, the body produces antibodies to the tumor and rejects it.  The HLA antigens found on cancer cells reveal the cancer’s identity and also the chromosomes making the protein HLA antigens.  In Immunology parlance, these antigens refer to onco-fetal antigens.  Carcino-embryonic antigens found in lung tumors and ovarian tumors are onco-fetal antigens.  In Sir Harland Burnett’s theory of immune surveillance, cancer if fought long enough becomes attacked by the immune system and eliminated because it is non-host.  In reality, the drugs used in cancer chemotherapy destroy the immune system along with the tumor, and the patient, if they survive becomes susceptible to infection and dies of sepsis due to an impaired immune response. 

Back to the cell.  The 46 chromosomes in a cell are the product of millions of years of evolution from a single-cell entity, to a metazoan, and finally an intelligent animal.  This is why we have 46.  As carcinogenic agents destroy actively transcribing DNA primitive DNA from eons past starts to work, making protein antigens, and the cell trying  to survive, divides repeatedly.   The antigens present on the cancer cell membranes reveal the chromosome making the onco-fetal antigens.   Cancer cells can be immune-typed like tissue, with HLA antibodies.  The current dogma in Pathology of characterizing neoplastic tissue by chromosome mutation merely is the revelation of stochastic, happenchance destruction of actively transcribing DNA by chemicals.  It is this author’s opinion, that current Molecular Biology techniques used by Pathology are merely instruments used by professionals to bolster their income. 

Chemicals, even household chemicals if ingested produce cancer.  Metals like Chromium, nickel, and arsenic are revealed in Wikipedia as active causal agents.   Gamma radiation and alpha particles used in diagnostic medical research produce leukemia and lymphoma. Viruses seen in lower life forms produce neoplasia but this is a rarity and subject to another book.  Cancer if limited in growth by current antibiotic ribosomal agents or telomeres inhibitors eventually is rejected by the body’s immune system. Again, this is material for another book.  What I am speaking about is relevance.

If a human being does not want to get cancer, maybe they should not ingest chemicals. In modern society, this is more easily said than done as all food is preserved in the supermarket with either chemicals or metals.   Arsenic in pepper shakers happens everywhere.  Benzene, used to preserve hard liquor is everywhere.  Formula 409 and Mister Clean are potent chemicals that cause cancer if ingested, the list is endless and increasing.  The poor agrarian life of a farmer or food producer is probably healthier than an executive position in a skyscraper with lunch at a restaurant.  Please do not relegate this edition as ravings from Rasputin, the mad monk.   Rather, this is a lonely man who wonders how he can get a good buzz by himself of non-adulterated gin at the beach or by a long and winding river.  Maybe pot will do but this author does not like to get high.   Carry on and keep a stiff upper lip and maybe something will break.  HOPE SPRINGS ETERNAL!