Good Fat

The medical establishment and the FDA inundate the populace with admonitions about how horrible fat is to eat and that everyone should avoid a fatty diet like the plague.  A fatty diet causes heart disease, diabetes and premature aging.  The establishment tells everyone to eat lean meat although meat is about sixty percent fat.  A proper diet consists of lean meat carbohydrates and vegetables: a square meal deal.  This paper serves to educate the public on the proper consideration and evaluation of fat and its inclusion or omission from a good diet. 

There exist two different types of fat: good fat and bad fat.   Bad fat derives mainly from meat, including chicken which is said to include less fat.  Bad fat is saturated and usually contains upwards from 20 to 24 carbon units in its aliphatic chain.  Bad fat has no double bonds.  Bad fat is broken down into two carbon fragments via acetyl-coenzyme a and enters the mitochondrion for energy production or used to synthesize cholesterol and glucogenic hormones or bile acids. Logically we can assume that a diet high in bad fats will plug the vasculature on its route to storage in fat cells or lead to diabetes by indirect stimulation of cortisol synthesis.  These are the main pathways for saturated fat, others exist.  Living on a diet high in saturated fat ultimately causes premature death.  God intended man to eat meat mainly when the crops failed and/or in winter there was nothing else to eat.  

Enter good fat.  Good fat are hydrocarbon chains usually from 14 to eighteen carbons of length.  These fatty acids usually sport a cis double bond in the three position hence the name 3-omega fatty acids.  The double bond can occur elsewhere in polyunsaturated fats up to eighteen carbon units long as in linoleic acid.  Good fats derive from grain, nuts and vegetables. Good fats have an entirely different metabolic fate but can serve as energy substrate like bad fat. Good fats by way of their double bonds serve as functional groups in arachidonic acid hormone: hormones that govern vasodilation and cellular effector function. Animals fed on a diet deficient in good fat are sterile.   Good fats form brain fat in the form of ceramide and sphingomyelin.  These fatty phospholipids enable brain function and the brain cannot grow or function correctly without them.  We can logically assume that humans that live on a meat diet alone will exhibit hypertension and low intelligence.  The big kicker, the fact that will astound all readers is that the heart mainly relies on small to medium chain fatty acids for 60% of its energy requirements. This fact presents in the tome “Ganong’s Physiology”.  The heart requires fat to live a healthy life and that fat is good fat not bad fat and saturated fat will eventually plug this essential organ that essentially determines the length of our existence here on earth.  

Fatty acid metabolism is a treatise that consumes at least three pages in “Wikipedia”.   This essay serves as a premise and reminder that life is not complex and that eating a lot of good fat in nuts and grains will not harm us, rather it will extend our existence.  Strive to ingest that good fat that is also present in eggs, dairy and fish in excess to the bad fats present in meaty animal products.  I promise the life you lead will respond accordingly. 

Cholesterol

Cholesterol is the substance that gives rigidity to the cell membrane according to the hypothesis of the Daniella phospholipid bi-layer model.   It is produced by the body in small quantities in direct proportion to inheritance.   Some people produce very little cholesterol but the Pima Indians of North America produce a lot of it because they evolved as vegetarians.  Human beings absorb cholesterol from their foodstuffs especially those humans that consume much meat.  Human beings try to excrete cholesterol from their body in the fecal stream in the form of bile acids, bile acids are reabsorbed in the entero-hepatic circulation and reused in the body as membrane items and also modified into steroid hormones.  In general, the human body aims to eliminate cholesterol in the form of bile acids because in excess this yellow waxy substance plugs up the micro-circulation by forming myo-intimal plaques that block blood circulation and oxygen transport.  The effects of cholesterolosis or cholesterol poisoning are ageing, atrophy of the internal organs, stroke and heart attack due to paucity of oxygen transport in the heart.  

Chemical structure of cholesterol

Figure 1cholesterol

Figure 2bile acids

The race then in longevity is ingesting enough cholesterol to make steroid hormones but not enough to cause atherosclerosis.  Vegetarians live longer primarily because they do not ingest vast amounts of cholesterol present in meat.  The stool of a heavy meat eater is odorific and putrid while the excrement of a pure vegetarian has very little odor and is more voluminous.  In addition, the high content of saturated fats presents in meat through acetyl coenzyme A build a per phenanthrene molecule two carbons at a time making more cholesterol and bile acids.  One may assert that cholesterol is a main metabolite in the branching point of bile acids and steroid hormones.  It is essential to limit the amount of intake of cholesterol in meat and aim to excrete that which is absorbed by eating vegetable mass enriched in sitosterol, a similar compound that helps man bind and eliminate cholesterol.   

Figure 3cortisone

Cortisone, a steroid hormone similar to cholesterol, acts on the DNA of the cell, is transported to the nucleus of the cell and produces a net synthesis of mrna and DNA.   Cortisone governs the immune system, maintains cellular integrity and regulates glucose balance.  Sex hormones are similar but exist in a microcosm of action related to reproduction.   As scientists we see that some cholesterol is necessary for maintaining life but too much is anathema.  The current dogma of a meat-based diet including meat and vegetables is really a superposition of the meat industry to sell more product. A diet consisting of grain, dairy, and eggs seemingly would be much more healthful.  All animal products contain cholesterol but by net content, meat contains the most.  It is interesting to note that fish contains equal amounts of protein but half the cholesterol of land-based meat.  

It seems everything that God gives us is a two-edged sword, some is necessary, too much is lethal.  Only children who have to grow brain tissue and body mass really need meat in their diet. Adults do not.  Possibly, huge hulking football players and track stars may need a meat diet to facilitate protein teardown and turnover.  Whatever the case it seems prudent to eliminate intake of cholesterol by any means possible even if it means living on oatmeal and fresh cream.  

I don’t know why but it seems everything that is delicious and fun is either, immoral, unethical or toxic.  Why this is so I don’t know why but hopefully someday I will understand the true meaning of life.  Until then,  eat very little meat, a lot of vegetables, tithe your church and hope for the better in our turbulent tumultuous world.  

SuperChristmas

A long time ago when life was a new wonderment every day and the delight of growing up in a prosperous economy overwhelmed the senses, Christmas came into being once again.  There was the huge flocked tree obtained from the local supermarket and the homemade ornaments and the bright incandescent lights that shine all night because energy is cheap and the Christian family together in December. The cold, Crisp transparent evening with bright stars set in darkness that surrounds the houses that choose to decorate for the holidays comes into being and sets the stage for the upcoming new year.  Grandpa and Grandma are coming for Christmas dinner and they brought all the gifts last week and put them underneath the big flocked tree with a thousand lights.  Toys and chocolates and fruit boxes and clothes and everything a child could and ever would dream of owning. 

It is five o’clock and already dark and the white Ford Fairlane pulls up in front of the lighted porch on Bacon way.  Grandpa and Grandma get out of the car with big smiles.  Wracks and the Fonz stand in the front hallway waiting for them to enter. Louis is not a big man but he was but the two surgeries he suffered shrank him at least two inches and all that remains of his dark wavy hair is a bald head.  Grandma is petite with overly fine hair with a reddish tint to it.  They both wear thick woolen overcoats that define the cold weather in the coldest month of the year in California known as December. Grandpa takes the main reclining chair in the living and dining room, lights up a big Roi Tan cigar and puffs.  Smoke fills the room but no one cares because dad is a smoker too.  Grandma goes into the kitchen to help Norma prepare the Christmas meal and Grandpa reads the business page and studies the stock market.  The Wracks and the Fonz sit in the convertible sofa opposite the big reclining chair and give Grandpa Company while swilling two Roy Rogers alcohol-less cocktails made by Dad from his convertible bar over the television set.

Amerada oil booms grandpa from behind the business page

American airlines is the one to watch he states firmly afterwards.

It’s time to eat says mom.  Everyone come to the table.

The nicest piece of furniture at the Wracker house is the dining room table.  It is made of black walnut with all the French artistry woven in and with two planks inserted in the convertible chassis it can sit up to ten people.  Tonight it is six and the black table adorns with wedding china in white with roses and sterling silver cutlery, four pieces at each setting.  Pine cones form a Christmas centerpiece and each setting has a wine and a water glass in crystal.  Christmas fare is from Grandpa, he ordered specially a large eye of round roast roasted to medium rare because he felt that this was the most flavors filled cut not prime rib as most people assert.  Steamed green bean drizzled in olive oil, with a touch of Garlic serves as the vegetable and exemplifies the mounds of mashed potatoes made with fresh butter. For wine there appears a bottle of Cabaret Sauvignon and the kids get a quarter glass-full for Christmas. 

Everyone thanks God with the meal prayer and father raises his glass upwards and toasts to us.

Manga he says.

The food disappears and everyone has seconds and Grandma who sits on the left of the Wracks puts another helping of beef on his plate and tells him to finish it.  The family gorges on the fine food and then sits back in their chairs with big smiles on their faces.  Desert appears in the form of pie and vanilla ice cream.  Two eight inch pies appear on the table, one blueberry the other cherry and they divide up and partition across the table.  Then a decanter of fresh brewed Columbian coffee from a percolator is on the table and everyone has a cup with some fresh milk.   The dinner draws to a close and Christmas is almost done.  The china spaces evenly in the dishwasher and the silver ware is washed by hand and dried and put back in its own case till next year.  The Wracks clears the table and does the dishes as he usually does for every holiday festivity.  Each piece is hand dried and put in its place until next year’s Thanksgiving.  The older Fonz disappears as is his trick every holiday but will re-appear to say good-bye to the guests.  Grandfather and Grandmother sit in the living room in the French chairs around the Christmas trees and talk to the parents.   The Wracks sits on the floor, plays with some toys and looks in wonder at the beauty and finality and immortality at the event as it occurs once a year. The lights glimmer and bounce off the tinsel on the tree onto the ornaments hand made over the decade.  After about an hour of talk and relaxation the Grandparents announce that they are leaving.  The Wracks fetches their thick woolen coats from the hall closet.  The front entry is lighted and the red brick steps lead to the white Ford Fairlane with the small block v-8 that will eventually become the party truck of the Fonz.  The air is cold in December and the stars scintillate brightly and seem to say that this is a day for the king of Kings.  The Wrackers wave goodbye to Louis and Theresa and the white car turns in a driveway and chugs off down the street of Bacon way. The family withdraws and enters the edifice and turns off the lights in the kitchen and living room and the Wracks sits in the living room next to the tree and wonders.  After a while he extinguishes the tree and goes to his bedroom.  His father is smoking before going to bed and his wife has just recently quit.  Christmas is done for another year.

This happened before the dark times, before the dog, before the emergency surgery and the jet plane ride home.  The great learning never happened until many years in the future.  Christmas is a time where believers salute the birth of the savior who gave up his life for mankind.  What this means is nebulous to most but the ritual and the rite give credence and meaning to this worldly existence. The Wracks wants to thank all those who ushered him through and enabled him to achieve his senior years. Christmas is for giving, for charity, for tolerance of others and belief that a better life awaits sometime in the future. Thanks to all humanity that helped and have a truly, bounteous and merry Christmas.

Dinner with the DOW

Thanksgiving is a time of joy in thanks of giving of sustenance to others.  As is every year the Wrackers would invite people to share their thanksgiving with them. Norma was a gourmet chef and in her youth wrote a thick cook book that all people use and believe in day to day in this varied life.  The epicurean bible, from Norma gave us countless delicious meals that the Wracks will cherish in his memory until the end. 

In latter November it is cold as December is the coldest month of the year.  The Dow is scheduled to arrive at five thirty and have a parking space reserved in front of the house as requested by Marvin.  They soon arrive in an Acura limousine.  Marvin gets out of the car and helps his wife from the passenger side and together they enter the domain of the Wrackers.  He wears a grey wool worsted business suit with black loafers and a grey tie.  Barbara, red hair and all from a long time ago era, in a formal evening dress and matching handbag ascend the brick steps with a single white light on the corner of the fence.

I love my new Acura says Barbara.

I wouldn’t buy a Mercedes Benz because they are German.

The Japanese make good cars.

The Wracker house is small, and the family room is the dining room and the living room is reserved for guests only.  The Dow move in and sit on fine French wood chairs with cushions given by Grandpa.  The shag carpet is white and green and the large window frames the room on the street.   Barbara has a glass of wine and Marvin has bourbon whiskey.  Vincent converses with Marvin and Barbara while Norma cooks in the Kitchen with the help of Wracks. The Wracks sets out the sterling silver cutlery which is used only on Thanksgiving and Christmas and was a present from Theresa on the wedding day. Each setting has two forks, two spoons and a single gleaming sterling knife.   The plates are fine china to be washed by hand after the meal and set away for another year.  The table with a leaf seats eight but can hold up to ten people in a sitting.

Marvin has a stern look on his face with fine black hair slicked back to a style.  He was an honor student at Bolt Hall law school in California but every time he takes the BAR the board flunks him.  He now ostentatiously publishes a European train schedule book for American travelers.  Barbara doesn’t work. She never did and never has to as are the people who populate the upper crust.  Auburn hair and freckles and light grey eyes as is the forefathers of the constitution of the United States of America. What a pair and the Wrackers have them for thanksgiving. 

Dinners ready says Norma, everyone sit down. 

Large dishes adorn the Pass through and are full of savory food.   Green beans steamed with garlic and seasoned with extra virgin olive oil.  Gravy made from boiled turkey neck and heart and onions for hours on end.  Extra-large sweet potatoes the size of a fist abound. Turkey stuffing made with butter and done in a pan sits on the side. Vincent carves the twenty pound turkey with an electric cutting knife plugged into the wall.  The guests get up and are first and serve themselves, loading their plates with mountains of savory food.  When everyone finishes service, they sit down and pass around a fresh bottle of white wine. 

Who is better than us says Father Wracker.  Manga!

As in the true thanksgiving tradition everyone gobbles down their food and Marvin is the first one up to the buffet to get seconds. When everyone finishes, Mother Wracker brings out two pies, a pumpkin and a blueberry pie that she obtained from Marie Calendar restaurants

It’s too much trouble to make two pies on Thanksgiving with all the food so I bought them says Norma.

The Wracks brings in the dishes and proceeds to put the china in the dishwasher with the sterling separately on quick wash so they don’t chip.  The Wracks starts the dishwasher and proceeds to scour the turkey pan with steel wool and soap in the sink as he does every thanksgiving.  Marvin and Barbara disappear into the living room with Vincent and he and Marvin open a bottle of grand Mariner cognac and drink down shots Russian style.  The men talk, the ladies chat and time boils away and finally Marvin announces it is time to take the thirty minute drive to their exclusive retreat in Malibu.  Norma has disposable Tupperware filled with turkey and dressing and green beans and Marvin eagerly takes the offerings and puts it in the back seat of his car. He loves taking home leftovers of Norma’s cooking. Both Marvin and Barbara wave goodbye and drive off down Bacon Lane.   Thanksgiving is officially over but the house smells of roast turkey and the Wracks clears the cognac glasses, empties the dishwasher, puts the china back into its special place and loads the dishwasher for a second load with glasses,  casserole dishes and assorted bric a brac.  Father sits in his chair.  He doesn’t smoke anymore, because he had an abdominal aneurysm repair.  Living the fast life and taking stimulants and smoking and not sleeping eventually degenerate even the sturdiest body.  He chose the life he pursues so it is time he pays for his digress in spades. Thanksgiving is over and Christmas is in a month with another dinner on tap and whatever guests invite themselves to the festivities. The Wracks is happy because many people don’t have thanksgiving dinners with themselves or their families and buy a turkey dinner from the market, savor it on their own and go out to a bar.  There is more to Thanksgiving then the meal.  It is a day to salute God and offer salutations for the goodness of the bounty he bestows upon his people.    The Wracks is glad to have a thanksgiving and a family and a place to stay in our great country the United States of America and he wishes the best to all people who believe in hope and charity.  The Wracks walks outside the front door and looks at the stars and they blink and shine upon him and he prays and wishes that someday he will have a home all his own and a family to share thanksgiving with.  Satisfied with his day he closes the front door and locks it,  turns out the lights in the kitchen and living room, lets the dog out of the laundry room then returns to the bedroom he used to share with his brother who now lives elsewhere and the day ends and Christmas season begins.   

The last day of October

As the season transits, and the air gets colder, sunlight ebbs and harvest begins, embarks the last day of October.  Here, up north it is quiet, as it usually is and the green house with the Japanese where nothing seems to happen, and is never decorated for any holiday stands immutable to the sands of time.  They never give out candy to the young children that migrate in this little enclave.  So may time endure?  The house on the other side with three previous owners has two pit bulls, that are never seen, that lives in a garage viciously, and barks at the slightest provocation or noise.  The house opposite to the left, painted white has an absent owner and tenants that are not seen or heard.  They cut down all the flowers and roses that surrounded their house with the last owner and don’t decorate either or give out candy to the young costumed children. They live next to the two older women who drive one SUV and never use the front door; they only exit via an electric garage door.  The tenants in front of this house decorate for Halloween and have two kids with long hair and an older daughter that looks exactly like their mother.  Of Latino ancestry, they live with their grandmother who only comes out to put out their trash cans each week on a Tuesday.  Aside from the pit bulls barking, this neighborhood is quiet, like the silence before the storm, not ringed with frolicking children or busy industrious young adults who come and go and make their living.

Living across the street and housebound by chance and health the neighborhood is too quiet to be real.  It is too quiet to be ascertained too quiet to be believed and too quiet to the observed.  Tonight is Halloween and we will count the children who come and will receive a candy bar.  There is plenty candy to go round and there is always the leftover to be enjoyed.  Tonight is Halloween on a Sunday.  The Covid epidemic is winding down and soon the holidays will start and be enjoyed and signal another year of life to be chalked up as a success to the living who has survived. 

Five severed latex heads sit on the ground illuminated by ultraviolet light.  Over on the side yard on the Japanese side inflatables balloon and wave around the clock: a cat, a witch, and a goblin.  Seven more hours to go on this all hallowed eve until the end of the year and thanksgiving harvest ensue. 

Early tomorrow morning all the inflatables and outside décor will be retrieved and laid to dry out to be stored presently.   No more decoration till December when we celebrate the birth of the Messiah.  Time goes on, the silence runs deeply and the night beckons its darkest splendor and the year runs out.  This and more in the life in the new millennium somewhere in California distantly.   Time to look forward to the black market adds that will inundate the media starting at twelve and one A.M. in the dark of the night all alone. 

Windansea

There comes a time when a boy becomes a man.  It often does not occur in a bedroom, or in a van, or any special place.  A boy becomes a man when tossed into the elements, in the world, in a common place, in an extraordinary situation, all alone.  For a fifteen year old teenager, in high school, becoming a man meant riding big waves, radically, with commitment, for the entire world to see. For Wracks, his time comes now.

“Let’s go down to Diego, “says HP

“The surf is flat, I checked it myself,” says Cool

“There might be something coming in at staircase,” says HP

“Do you have smokes and brew,” asks Cool.

“We have smokes and brew, “promises HP, “I need company.”

“I have gas money,” says Wracks, “I’m in.”

“Get your gear and throw it in back,” orders HP.

Kool has a green Meth model shaped like a teardrop, and a green robe and a duffel bag filled with goodies and he tosses them all in the back hatchback of the yellow and white Volkswagen van.  Wraks has a purple and red second hand NatPro purchased for a song from Bee aye the seventh member of the room.  HP has a red pintail BK potato chip.  Wracks has drilled out the glassed in fin on his purple monster and installed a neon orange large fin of his own design.  The result yields a blatant diamond tail billboard meant to handle large surf.  He delicately places his board in the back of the van along with his blue druid robe and a sack of food liberated from his parents house.  The ride down to Diego bodes long and boring and Wracks falls asleep, like always on the bed in the back of the van as the tuned exhaust blare a blatant note of existence. 

Kool drinks a Budweiser sixteen ounce in a huge gulp, finds someone to throw the can at and heaves the crumpled mass at them on the freeway.  The can bounces off the windshield of a sedan, the sedan swerves and an angry driver displays the finger to Kool.  Kool displays the finger back and grabs a cigarette, then lights the Marlboro with a Bic butane lighter, smiles and draws a huge puff from the reefer. The who blares from a tape deck suspended from the metal dashboard of the van and time passes.  Smoke drifts in eddies out the side exit windows and the town of little happenings comes into view.  Looking down the cliff, the three surveys the beach break with rocky reefs interspersed amongst the long expanse of sand.  The waves break at two to three feet with a light wind blowing the soup into a delicate froth of soup.   

“Let’s go to seven eleven.”  Says HP “ I am hungry.”

“Yeah dah.” Screams cool,   “Hamburger, candy and a huge slurpee to go for me.”

The yellow white van growls into town and the first 7-11 looms in front of it.  HP pulls in, he and Kool exits the car and go inside the store.   They both return with brown bags and large slurpees in blue and red cherry.  Wracks eats his bread, a packet of Kraft cheese bits  and savors a can of red sugared coca cola. 

“We are going to Windiness, “   smiles HP

“The cashier inside the 7-11 says that a hard south swell currently focuses on Windiness and the surf should be larger there. “

“I have never been to Windiness,” says Wracks

“The break appears to be a deep water reef close to shore and the waves break right and left depending on the season and the swell direction.” “It is only fifteen minutes more, over the bridge, at the entrance to Diego Bay.  A colony of small house situates there and the person told me where we could park safely.”

Over the grey steel bridge and into the southern part of the niche, before Crown beach go the three surf riders with hopes, dreams and ambition.  In ambition, comes excellence and today the excellence tests under the envelope of big.  Windiness beach looks like a short beach strewn with rocks, typical of southern California beaches.  Windiness sets straight like a flat beach break except here, south of The Niche, the bottom of the ocean a hundred yards out dives deeper than one thousand feet.  For this reason, ocean swells attract to the reef and rear up suddenly out of the deep water and break hard with much mass and water coming over  with the breaking wave.  Wrack’s looks out the side window of the van and Windiness, today breaks at over fifteen feet in height.  A tall man in a white helmet and long surfboard enters a huge swell and turns his huge board and banks toward shore on the huge wall of water.  The wave at Windiness rears up as a huge triangular peak and breaks in both directions. On this day the lefts break better.  A slight offshore wind makes the surface conditions epic in nature and the waves carom to completion with spray dancing off the top of the breaking waves.

“I think the waves are too large for me,” whimpers Wracks

“We are parking and you are going out,” screams HP. “The conditions are epic and half of Diego watches on the beach.  If you start to drown, they will call a helicopter.”

“Twisted,” screams Kool and the crowd on the beach turn their heads for a second and look at him. Kool tears his clothes off like a man possessed and stark naked pulls on his wetsuit like a hotdog stuffing machine.  Today Windiness breaks like big Pipe and Kool rides goofy foot.  Both HP and Kool prepare with amazing speed and run toward the entry spot on the beach.  They both run to the water and cast themselves out like torpedoes steaming out of a submarine.  Wracks  remains stolid and slowly waxes his board and counts the set waves.  The sets are four in number with the second wave the largest and the sets periodically appear at twenty minute intervals.  Wracks’    decides to paddle out.  At windiness, a channel to the right of the reef sucks water out in a huge riptide when the waves break large and wracks enters the entry zone and the rip aids the paddle out into deep water and big waves.  Out in the middle of the ocean, an extraordinarily large set hits the reef and Wracks gets caught inside the area where the wave breaks and loses his surfboard, comes up after the set and finds him in the middle of nowhere in twenty foot plus waves.  He sees the older man in a helmet and asks him for help.  The older man says,

“Son, in big surf, you have to swim in.  If a rip pulls you out the only way in is to body surf the waves in.”  Wraks again asks him to help him in.   The man in the helmet repeats his command. “Body surf the waves in,”  “It is the only way. “

In large surf the ocean heaves in turbulence and without a wetsuit, most people soon drown.  Wracks  starts to back stroke his way into the beach.  The riptide hinders his exit.  A huge set hits the reef.  Wracks turns into freestyle stroke and scratches hard to enter the ten foot high wave.  The wave picks him up and Wracks hydroplanes down the face of the wave using his hands like fins  At the bottom of the wave, Wracks turns and points toward the open area and the wave overtakes him and pushes downward, deeply and the turbulence spins him around like an old rag doll.  When deep under water all watermen open up their eyes.  Watermen open up their eyes to see where the bubbles go.  Where the bubbles move signals the direction up.  Wracks swims in direction of the bubbles, breaks surface, and gulps down a huge amount of air.  A second wall of white   water hits his body and Wracks goes underneath again.  Watching the bubbles, he swims upward and breaks surface again.  The set of waves concludes and Wracks has been pushed inside towards the beach and exit from the breakers seems possible.  Within ten minutes, wracks scrambles up on the beach and looks for his board.  Some kind of observer rescues his board from the rocks and sets the purple explosion on a safe stretch of beach.  Wracks sits  on the beach and looks again at the breaking waves.

“It wasn’t so bad,” he thinks, I am going back out.”  

Wracks’ grabs the reins of his horse, gets back on and rides again.  Luckily, no huge close out clean up sets made him swim in again.  Both HP and Cool surf as the time of their lives on the left breaking waves, just like Pipeline.  Wracks surfs the rights which break slower and mushier but still huge in size.  Wracks’ gets three huge set waves presently, and successfully performs two rollercoaster reentries in double overhead plus surf.  Wracks notes that the bottom turns feel good with the large custom fin.   By three o’clock PM. HP waves from the beach and heads up to the car at a parking place that mysteriously appears out of nowhere for the three at this exclusive and fabulous colony community.  The three exhausted wave riders strip their wetsuits and dress slowly.  Then the three sit inside the car and devour whatever remains of food in the car at hand. 

“That was epic,”  says HP “Awesome radical lefts.”

“Tubular,” asserts Kool as he smiles largely and eats a two foot long beef stick.

“I got two really good ones,”  says Wracks  “I can’t go left yet.”

“I have to work tonight, “ says HP, “lets go.”

The white and yellow van roars to life as the megaphone exhaust shakes and belches mist out of the header.  The van rolls over the bridge, gets on the interstate five and the three head for home.  HP smokes cigarettes, drinks a coca cola and drives.  As usual Wracks falls asleep.  Kool chain smokes and drinks a Budweiser red sixteen ounce beer.  Wracks  wakes up at the refinery, and again at dismal canyon road, past the high school.  At the corner of Deadman’s lane, Bacon way and Saint Inez sits the Wracks house, with grandma, the dog, and a little bit of home.  Wracks and Cool pull their gear out of the van and Cool takes his board and duffel and disappears down the street towards Marco’s way.  Wraks rinses off his gear with cold water and enters his house.  The little dog wakes up, yelps and seems to smile.  No one resides within except for grandma who sits in her room and watches Lawrence Welk reruns.  She wave at wracks and smiles. 

“I will make dinner in fifteen minutes,”  says Wracks

Wracks finds some chicken with wine left over in the refrigerator, and puts the mass into the microwave oven.  The oven hums, the dog runs in his sleep on the cushion, the house darkens as light leaves the remains of the day, and night in tranquil hills begins.  Here nothing becomes of what it seems.  

Wracks never rode the waves at windiness ever again.  The drive remains too long especially for a person who does not own a car.  The secret of windiness remains.  When a huge storm turns off the coast of Antarctica, in the west, extreme south swells focus on south facing beaches on a north stretch of land.  A huge offshore canyon at windiness captures extreme south swells and Windiness can be twenty feet when everywhere else looks as flat as a lake.  Everywhere of course, except Jalama and the extremely well kept green custom houses last another day in a time when darkness and immensity threaten the world and the intrinsic fabric of mankind. If a wave rider surfs windiness, watch out for great white sharks as Simmons disappeared mysteriously there one day in big surf.  This is one of the magical surf breaks on the California coast.  Normally a winter break, in the summer if the south swell is right, it achieves immense size.  Wracks was there to surf it.  The other magical surf spots are Newport Point and Malibu on a big west swell.   When trestle is huge, Malibu is better.   They guard Newport Point with M16 rifles. 

La Heim

With the AMA controlling medicine and telling physicians what to prescribe and what to do, everyone is forced to comply or go elsewhere.   If physicians don’t comply, they get their licenses revoked. The question remains, what tactics should the people employ to live a long life of high quality.  Is current allopathic medicine charlatanry that actually shortens the lifespan or impinges the quality of life in a negative fashion?  The factors that shorten a lifespan are the following:

Infections

Toxins

Cholesterol

Lifestyle.

The concept of infectious disease is self-explanatory.  Bacteria, viruses and parasites are the causal factors.   Strep infections of the lungs and staph infections of wounds seemingly are the mainstay of bacterial infections.  With appropriate hospitalization, penicillin’s and lots of money, most people survive these maladies.  Esoteric bacterial infections with fastidious species, with the advent of antibacterial treatment, are now curable.   A hundred years ago plague or Brucella or Salmonella would cause fatal disease but now with appropriate therapy people survive to achieve their genetic potential.  Viruses and most enteric infections transmit through fecal contaminated foodstuffs and hepatitis A, B, and dysentery are rarer today with the use of current food treatment and preservation.  However, most restaurants and fast food parlors do not wash their vegetables and now people are acquiring chronic parasitic infections not prevented by preservatives.  Untreated fruits and vegetables harbor snail eggs, worm eggs, and parasitic cysts that become motile worms once in the intestinal tract.   In women this is seen as midriff bulge and in men with chronic parasitic infections, pot bellies.  This all begins around age forty and accumulates and progresses with each decade. Preservation saves mankind from bacteria and viruses but at the same time fills the body of man with metal salts.

All metals if ingested accumulate in the body and cause chronic disease.  Examples of chronic disease are diabetes, hypertension, renal failure and arteriosclerosis.  All processed foods and restaurant faire contain metal salts.  Heavy metals like lead, and transition metals like iron when emulsified into processed food prevent bacterial growth.   These agents are known as preservatives.  How long has salad dressing lasted in your refrigerator without spoiling past the expiration date?  Three years or five years is not unusual for processed food to be palatable and edible.  Any metal when consumed accumulates in the arteriovenous tree causing arteriosclerosis, hypertension and stroke.  Organic toxins from flowers, mushrooms or reptiles are much harder to spot and an acute admission to the hospital necessitates high pressure liquid chromatography to elucidate the cause. 

The most insidious factor that curtails a long life is cholesterol.  Cholesterol is found in all meats but less so in fish.  Milk and eggs have significant amounts of cholesterol but not nearly the amount found in meat.  Cholesterol is a yellowish brown buttery, sticky substance that clogs up arteries causing heart attacks and venous embolus.   Cholesterol is necessary as a rigidity factor in the cell wall, like rebar in concrete to make the cell wall stiff.   The body produces just enough cholesterol to maintain itself.  Because of this fact, cholesterol recirculates in the blood from the gut in what is known as the enterohepatic circulation.  When a human eats cholesterol rich food like meat, the cholesterol recirculates in the lymph and blood until it is excreted in the stool or deposits in the muscular element of arterial circulation.  The main reason to ingest vegetable roughage is to bind the cholesterol, eliminate it and prevent its recirculation.  The high protein benefits of meat are overshadowed by the deleterious effects of cholesterol accumulation.   We all love out rib eye steaks but the solution to a long life is to eat less or no meat and lots of beans, oat meal and cheese for adequate protein nourishment.  Mexicans living on beans and tortillas all develop marasmus so it is necessary to eat meat, hopefully that will be fish.  This all depends on geography and religious preferences.

Lifestyle is the final topic of this dissertation.  It appears that an active lifestyle is conducive to longevity

Office workers and heavy meat eaters all die of cardiac disease, especially if they smoke or take drugs.  The epitome of a successful life is to exercise in the spare time from an occupation and meditations like yoga, Pilates, tai chi or aerobics are mandatory to maintain the euphony of the organism. 

Most people want to live a long time.  Chelation therapy removes metal from the body but is lengthy and very expensive.  Parasite de-worming is one of the most overlooked aspects of modern medicine because most people don’t want to examine the stool of others and a protuberant abdomen should suffice to acknowledge the infestation by enteric parasites.  Eating a vegetarian type of alimentation or at least limiting meat intake and resorting to fried chicken will add at least a decade of quality life to the existence. The ticket is to consult physicians proficient in these therapies.  Those that want to live forever consume gold thiol-malate or resort to Egyptian life extension practices or undeniably so become vampires.  I believe it is the quality of life that paramount’s existence. The rest is in God’s hands so take it for what it is worth. Most churches are open every day so believe and join those that embrace ethos over pathos and the word of the prophets where ever you are.

Statins or Sarin

Lipitor (Atorvastatin Calcium): Uses, Dosage, Side Effects, Interactions,  Warning

Back in the stages of an early reality, Chemistry 24 or Basic Biochemistry appeared as a prerequisite at the University of California.  The majority of this introductory class focuses on enzymes, their structure, their function and their chemical properties.  Enzymes are folded polypeptides that enable chemical reactions that would not occur naturally to proceed with rapidity and finality.  Each enzyme has an active site where the molecules orient to coerce a chemical reaction and an allosteric or binding site where the majority of the chemical molecules position before the reaction takes place.  After the primary chemicals line up on the enzyme the product dissociates from the allosteric site due to a decrease in intrinsic binding to the amino acids that form the allosteric site.  New molecules then diffuse out of the milieu to take their place and the reaction repeats itself rapidly.   An enzyme can increase the rate of reaction of a chemical process almost a million fold like Carbonic Anhydrase, the fastest enzyme ever studied.  The cell has a plethora of enzymes within that catalyze basic metabolic processes and also the processes that the cell type is noted for.  A majority of the class in Introductory Biochemistry studies enzyme kinetics and the types of inhibition that affect the rate of chemical processes studied.

The basic types of enzyme inhibition are reversible and non-reversible.  Non reversible inhibitors bind covalently to the enzyme, usually its active site and cause a permanent change of conformation that abolishes the enzyme function.   An example of this type of inhibition is the nerve gas agent Sarin.   Sarin is a fluorophosphates that reacts with the serine molecule of the active site of acetylcholinesterase, rendering the enzyme completely non-functional.  Clinically this appears as a nervous system short circuit with convulsions and respiratory paralysis.  Sarin is a non-reversible agent.   On a graph of enzyme activity versus inhibitor concentration, the curve is sigmoidal and logarithmic to the negative ln function. 

Reversible agents come in many different varieties. Some reversible enzyme inhibitors resemble the substrate of the enzyme to such a degree that the inhibitor competes with the active molecule in the milieu in proportion to its concentration within the cell.   The inhibitor looks like the substrate but catalysis doesn’t take place, the inhibitor dissociates and if a natural substrate is present, it binds and the reaction proceeds.  If the competitive inhibitor is in high enough concentration, it will shut down all reactions on the enzyme in the cell.  Removal of the inhibitor renders the cell reactive and metabolism proceeds.   On an activity versus inhibitor concentration graph, this type of inhibition looks like a straight line with an x and y intercept activity proceeding from high to low. 

Another type of reversible agent binds to the allosteric site on the enzyme and by stearic interactions and hydrogen bonding occupies the majority of the enzyme site and prevents substrate from diffusing from the milieu to the enzyme due to its intense binding by non-covalent interactions.  A graph of enzyme activity versus inhibitor concentration shows another straight line schema but with a steeper negative slope and x intercept closer to zero.  This description is enzyme inhibition simplified so even a novice can understand it.  The purpose of this paper is to illustrate that the current Statin agents prescribed by the AMA are reversible agents of the latter type that bind to an enzyme by hydrogen bonding and van der walls interactions and won’t let go.  Then result is death of the cell. 

The main statin of interest is Lipitor.  Lipitor and its myriad of patent analogues bind to the allosteric site of the enzyme hydroxyl-methyl-glutamyl-coenzyme A Synthetase; or HMG-Coa synthetase for short.  Hmg-Coa becomes mevalonate which is a steroid synthesis intermediate that forms cholesterol. This is the reaction that is inhibited.  Lipitor is said to prevent the formation of cholesterol thus limiting current atherosclerotic processes in the body hence less stroke and heart attack. The problem is this: mevalonate forms estrogen and androgen the sex hormones which means you become sterile with less libido.  Mevalonate also forms 21 hydroxy keto steroids like cortisone which affect vascular tonus of the mesodermal arterioles and glucose level in the blood which means the heart can’t beat as hard or fast and the pancreas fails to produce  the hormones insulin and glucagon.  In addition mevalonate also forms aldosterone, a potent mineralocorticoid that acts on the distal renal tubule to reabsorb sodium.  The body under Lipitor administration loses sodium in a diuresis and the kidney can’t work properly.  The only benefit of Lipitor administration is the liver will produce less cholesterol and bile acids for the systemic circulation and this benefit is transitory as the poisoned liver cells will ultimately fail and cause a pan lobular hepatic necrosis also known as cirrhosis of the liver.  Inhibition of mevalonate formation affects many different cell types and myriads of reactions in the body

The body naturally gets rid of cholesterol by secreting it with bile acids into the intestinal lumen.   Because cholesterol and bile acids re-absorb in a enterohepatic circulation,  the only way to excrete cholesterol is to eat tons of roughage that contain sitiosterols or chemicals that bind bile and cholesterol and excrete the steroids into the fecal stream. Lipitor will prevent the formation of cholesterol but will also inhibit other bodily processes to the extent of morbidity and/or mortality of the host.  Enzyme inhibitors as a generality are metabolic poisons.

In nature, in man, the pharmacologic agents that function well are structural analogues or receptor blockers.  Structural analogues for natural chemicals follow stoichiometric laws, don’t accumulate and the enzyme inhibition is proportional to concentration and reversible.  Receptor blockers turn off the signals that the brain and the organs give to initiate a chemical process.  This type of fine tuning is not as drastic or catastrophic as enzyme inhibitors with high degrees on allosteric binding.  Structural analogues and receptor blockers are the agents of choice for the manipulation of metabolic processes in the image of God called man.

Enzyme inhibitors are another product of an industry that gleans billions of dollars annually from Medicare in a patent medicine with a thirty year lifespan.   If a person has the genetic haplotype of a Pima Indian or the genetic defect of hyperbetalipoproteinemia, than this drug might have some benefit but these people are a minority, Hence Lipitor is an orphan drug.   The only rational treatment for high cholesterol is to stop eating meat except for fish and consume large amounts of vegetables with roughage to soak up the cholesterol.  May mankind have the courage and the intelligence to realize the truth and act accordingly? 

Making Carcinogen

The pharmaceutical industry is a trillion dollar cartel of corporations that make the medicines that Medicare and OASDI pays for.   The pressure in the industry is creating novel agents that evoke a patent that runs for thirty years.  This is to say, all people that make the medicine must pay royalties to the patent holder.  Pharmaceutical companies employ organic chemists who put together new and novel molecular arrangements on a host nucleus that evoke a new patent issue.  The race is on to produce new analogues of older offerings so the people think they are receiving the bounty of our society’s new technologies and synthesis.  In reality what the government pays for is multitudes of medicines configured as carcinogens that the working class ingests chronically.   The result is that people are not dying from age old illnesses but instead are dying of cancer.  A diagnosis of cancer eventually bankrupts the patient with therapies of marginal benefit and immense cost.  The result is retired people spending their life savings on Medical care and ending up penniless and on Medical.  The purpose of this paper is to show the multitude what the rich and influential are doing to augment the return on their hedge funds and municipal holdings.  The people working together cannot be thwarted by wealth of immense proportions.  A little knowledge can set you free.

What the industrial chemists are doing is building molecules with biological significance.  In the lab, chemists slowly link chemicals together and form new agents.  The easiest way to make a ring structure in the lab is to use organic nitrogen ion and add it atom by atom until the linear molecule cyclizes.  Nitrogen has an extra pair of unbounded electrons that make it easy to create linear arrangements and ring structures.  These sp2 hybridized electrons look for positive atomic centers on carbon atoms and link readily.   The result is a polyamide ring structure that resembles an organic molecule. In nature, God makes ring structures with carbon and uses one nitrogen or sulfur atom to cyclize the structure.  Rings with several nitrogen’s have unbounded electron pairs and readily add to macro-lecules like DNA.  The result is DNA bound to nitrogen rings and the bound DNA cannot open, close, replicate, repair or translate.  The result is a cancer with few tumor specific antigens, similar to stem cell neoplasms.  Pathologists are now finding these cancers with new genetic defects as a result of binding to chemical rings.  The author will illustrate the preceding assertion with examples of current available medicines.  Any medicine with a cyclic polyimide or amide ring structure is a potential carcinogen.  Here are the facts and the race is on. 

Prazosin is an alpha-1 blocker medication designed to treat high blood pressure. It has a low incidence of side effects.  It causes primarily with chronic use non-Hodgkin’s Lymphoma or cancer of the heart. 

Minoxidil is a prescription agent use for the treatment of high blood pressure and hair loss.  This agent also has a paucity of major side effects

Niclosamide is a medication used to treat tapeworm infections.  The major side effects are vomiting and abdominal pain.  With prolonged use it causes cancer of the colon.  Unlike other newer medications, it has a nitrate tail which makes it along with other nitrates a Trans version agent that causes genetic mutations and cancer. 

Triamterene is an effective potassium sparing diuretic use for high blood pressure.  Common side effects include depletion of sodium, folic acid and calcium, nausea and dry mouth.   It can also cause kidney stones.   It causes cancer of the kidney.

Hydrochlorothiazide is a diuretic medication used to treat high blood pressure and edema.  Side effects are decreasing kidney function and pancreatitis and high blood sugar.  It has the history and notoriety of causing primary cancer of the pancreas in addition to severe diabetes mellitus.  Doctors still prescribe it readily today!

It’s about time that the affluent and well-off have the chemists of the people build ring structures with carbons one atom at a time as God intended rather than using free radical processes.   This author feels that the establishment and powers that be, conduct such behavior in an effort to not pay pension benefits for retired wage earners.  They have all died of cancer.  Maybe some religious and altruistic people will have some compassion for the multitude wage earners and respond appropriately.

Food Preservation

In the order to increase corporate profit and minimize losses, the establishment preserves food.  Dried and processed foods have storage lives that exceed one year.  How is it possible food will not be decomposed by microbes during storage resulting in a product that must be written off in the books as spoiled and unusable.  In addition, customers return decomposed food and the corporation must pay the transit fee, inventory loss and destruction cost.  The answer why food lasts so long on the shelves at supermarkets is that it is preserved.  The way the corporation preserves most food is with metal salts as microbes cannot metabolize metals. Metals as they accumulate in the body cause kidney failure heart disease and more.  The population at large does not have the time or money to live on fresh meat and steamed vegetables as the rich do.  The multitude lives on preserved food so they can maintain their existence as employees and educate their children.  What can we do about it to give our lives a healthier and more productive existence?  The corporate mentality argues that food preservation is necessary because without it, waves of food borne microbial illnesses occur and afflict the nation. The purpose of this communication is to establish ways to preserve food without affecting the health of the people.  End stage disease costs the nation billions of dollars and year in health costs and ultimately bankrupts all the working class.  Let me begin.

This paper suggests a series of experiments that must occur to establish substances that can preserve food with relative safety and low toxicity.  The transition metals of interest are copper and zinc and the alkali earth metals are calcium and magnesium.  Calcium and magnesium are the first choice to use as food preservation agents.  Calcium is present in bone and exists as the Calmodulin contractile system of muscle.  Magnesium is the active cofactor ion of ATPase which is the currency of energy production. The transition metals of copper and zinc are possible sources as copper is a cofactor in ceruloplasmin brain metabolism and zinc is a cofactor for the B vitamins.  Aluminum is another possible agent for preservation but toxicity studies are in order to further characterize this amphoteric hydroxide moiety. 

The experiment to elucidate which are the best agents follows.  With a one molar solution of the chloride anion salt of the cations as base solution, make serial dilutions tenfold in a series of tubes of tryptic soy broth, a substrate which grows most bacteria abundantly.  Inoculate the series of each salt broth with a stock ADCC isolate of staphylococcus, a gram positive and E.coli, a gram negative which are indicator species and are found in most spoiled foods.  After 24 hours of incubation notice which broths are most antimicrobial by the intensity of turbidity also called opalescence?  The end point of antimicrobial action is the series dilution of the tubes that remain transparent.  From this simple experiment, the corporate structure can see which metal salts are most efficacious in their antimicrobial action.   They might decide to use the most effective agents in combination with one another.  Then corporate can lace their food with these least toxic metals to preserve them and ensure a longer shelf life without detriment to the population at large.

It says in the good book that everything that mankind needs to ensure a healthy and happy life is right in front of them, but they must search to find it.  It is these boldly empowered intrepid souls, the shakers and movers who make the world a better place to live in that we salute and acknowledge.  We can’t get very far without them.  Thank you and have a good day.