In Hebrew, ab means father or leader and ib has no definitive definition in Hebrew lore or the bible. In Sanskrit, ib means elephant or big thing. The current nomenclature of the new immunologic acting drugs end with a suffix of ib or ab. The best illustration of how the immune system works is in Sir Harvey Burnetts book, “A theory of Immune Surveillance” In a nutshell the immune system is an intricate organ that eliminates foreign invaders from attacking the self and it has links to the coagulation system, the complement system, and the kallikrein system. In boomer heavy lingo, the immune system is an immaculate organ that should not be interfered with in any way unless a clinician can augment its action. Why then does Medicine use monoclonal antibodies to treat auto-immune conditions?
To make monoclonal antibodies a patent protected animal is injected with the human antigen or tissue in question, and after an immune reaction ensues and perfects, the animal is sacrificed and the plasma fraction of its blood is passed in a special Sephadex column to remove pure antibodies. Nowadays these antibodies are directed against the human immune system. Idea becomes that the antibody will attack the cells causing the disease and the complement system. will eliminate the cells, hence no disease. The monoclonal antibody produced usually attaches to the Fc portion of antibody in solution or attached to B and T cells and this action eliminates autoimmune disease. In reality what happens, the monoclonal antibody attaches to B and T cells, destroying the functional immune system after complement kills the cells, and the patient or subject, deprived of a functioning immune system dies from a mold or bacterial infection. If an infection doesn’t kill a patient, monocytes, Kupffer cells from the liver or hunter-killer cells without intrinsic antibody regulation proliferate forming granulomas, similar to a tuberculosis infection and the patient dies from obstruction of a viscus or a growing granuloma with Langham’s giant cells creating a stroke.
Auto-immune phenomena usually appear after the thymus involutes after age 18. The Thymus makes thymosin, a hormone that stimulates T-helper cells or T-tolerizing cells to augment antibody production to the appropriate antigen. WHY NOT JUST GIVE THE PATIENTS INJECTIONS OF THYMOSIN? Thymosin is a three amino acid peptide hormone that can be synthesized commercially. Other immunomodulators that haven’t been studied are levamisole and Freund’s adjuvant. The impetus of this communication is to state that auto-immune disease or conditions are not treated by destroying the immune system. Back in prehistoric times, the professors in my lab studied Anti-T serum administration to destroy the T cell population thus hindering help or in the case of study low zone tolerance. The professors would never disclose how they made anti-T serum because its effects on the immune system are catastrophic and so is ib and ab pharmaceuticals.
Patents usually run in the pharmaceutical industry for 35 years and can be renewed once, allowing pharmaceutical companies to make billions of dollars feeding on the SSI health care fund. Today is like the 1920’s when the FDA formed. All medications that aid mankind benefit mostly, the people who hold stock in the companies that manufacture them. All medications that survive the patent eliminate because they are now non-profitable. A case in point is chronic heart disease that impinges on the auto-immune question tangentially. Back in the 1800’s heart patients drank a dilute solution of opium when they experience angina, and chewed chewing tobacco for the nicotine to make their heart beat when it started slowing down too much. The good old days are long gone with women in petticoats and little girls in pretty pig tails giggling at church. Nowadays, heart patients undergo a barrage of invasive tests and take organic chemical prescriptions that cause cancer, and the government pays the enormous costs of secondary and tertiary care medicine in the elderly. There is no room for the old and nicotine is a hazardous drug like cocaine, heroin and LSD, so go figure. Tinsley Harrison, one of the unknown greats who devoted their lives to eliminating suffering in humankind said,
“Let us not forget the old just for the sake of the new”. The new are patent rights that benefit no one but the wealthy and the old are the dreams of working man to make a life for themselves in our so-called classless democracy. Let me iterate once and again that the immune system is nothing to be meddled with, only added to and the educated professionals to read Sir Harvey Burnett.
Knock on her door and ask her why
Offer a piece of apple pie
Wake up from another dream
I don’t know and I don’t care
Life is an elegant symphony
Life is an elegant symphony.